Vesting period
Share granted period
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period
Upfront cash payment received
Upfront Cash Payment
Upfront cash payment.
extended lease term
Extended Lease Term
Extended lease term.
Segments
Segment Reporting, Policy [Policy Text Block]
Commitment And Contingencies [Table]
Commitment And Contingencies [Table]
Commitment and Contingencies
Repayment of loan issued by stockholder
Repayment Of Loan Issued By Stockholder
Repayment of loan issued by stockholder
Research and development tax credit carryforwards
Operating Loss Carryforwards
Operating Loss Carryforwards, Total
License H [Member]
License H [Member]
Percentage of patent prosecution and maintenance costs
Percentage Of Patent Prosecution And Maintenance Costs
Percentage of patent prosecution and maintenance costs.
Convertible preferred stock, shares authorized
Temporary Equity, Shares Authorized
Auditor Location
Auditor Location
Deferred revenue
Deferred Revenue
Deferred Revenue, Total
Operating expenses:
Operating Expenses [Abstract]
Finite-Lived Intangible Assets by Major Class
Finite-Lived Intangible Assets by Major Class [Axis]
Asset Class
Asset Class [Domain]
Loss from operations
Operating Income (Loss)
Concentration Risk Type [Domain]
Exercise Prices Range 5
Exercise Prices Range 5 [Member]
Exercise Prices Range 5.
Denominator:
Weighted Average Number of Shares Outstanding Reconciliation [Abstract]
Entity Emerging Growth Company
Entity Emerging Growth Company
Convertible Preferred Stock
Preferred Stock [Text Block]
Convertible Preferred Stock
Convertible Preferred Stock [Policy Text Block]
Disclosure of accounting policy for convertible preferred stock.
Income Tax Disclosure [Abstract]
Organization Consolidation And Presentation Of Financial Statements [Table]
Organization Consolidation And Presentation Of Financial Statements [Table]
Organization Consolidation And Presentation Of Financial Statements Table.
Schedule of stock options outstanding for employees and non-employees
Share-based Payment Arrangement, Option, Exercise Price Range [Table Text Block]
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Shares available for issuance
Outstanding, Beginning Balance
Outstanding, Ending Balance
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant
Marketable Securities
Marketable Securities, Policy [Policy Text Block]
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Exercise Prices Range, Lower
Share-based Payment Arrangement, Option, Exercise Price Range, Lower Range Limit
Non-cash consideration for licensing and collaboration revenue ($0, $7,500, and $0 from related party, respectively)
Non Cash Consideration For Licensing And Collaboration Revenue
Non-cash consideration for licensing and collaboration revenue.
Acquired in-process research and development
Research and Development Expense, Software (Excluding Acquired in Process Cost)
Deferred revenue, net of current portion ($100 and $50 from related party)
Deferred Revenue, Noncurrent
Deferred Revenue, Noncurrent, Total
Geographical
Geographical [Axis]
Common stock, par value $0.0001 per share 300,000,000 and 28,933,380 shares authorized at December 31, 2021 and December 31, 2020, respectively; 60,263,158 and 9,710,829 shares issued and outstanding at December 31, 2021 and December 31, 2020, respectively
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Entity Address, State and Province
Entity Address, State or Province
Share-based Payment Arrangement, Option, Exercise Price Range [Table]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Term
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Term
Term of grant
Shares Outstanding
Share-based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding
Share-based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding, Ending Balance
Share-based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding, Beginning Balance
Total liabilities
Liabilities
Schedule of Disaggregation of Revenue
Disaggregation of Revenue [Table Text Block]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Risk free interest rate
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule of Other Receivables
Financing Receivable, Past Due [Table Text Block]
Indefinite-lived Intangible Assets
Indefinite-lived Intangible Assets [Axis]
Private Company License Agreement
Private Company License Agreement [Member]
Private company license agreement.
Class of Stock
Class of Stock [Domain]
Significant Agreements [Abstract]
Significant agreements.
Issuance of Series C convertible preferred stock, net of issuance costs of $6.2 million (in shares)
Temporary Equity Stock Issued During Period Shares New Issues
Number of new stock classified as temporary equity issued during the period.
License and Collaboration Revenue
License And Collaboration Revenue [Member]
License and collaboration revenue.
Preferred stock shares issued
Convertible Preferred Stock, Shares Issued upon Conversion
Net Loss
Net Loss
Net Income Loss Available To Common Stockholders Basic And Diluted
Net income loss available to common stockholders basic and diluted.
Weighted-average common shares outstanding, basic and diluted
Weighted Average Number of Shares Outstanding, Basic and Diluted
Stock Options
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]
Fixed assets
Fixed assets
Deferred Tax Liabilities, Property, Plant and Equipment
Employer contribution
Defined Contribution Plan, Employer Discretionary Contribution Amount
Non-cash consideration for licensing and collaboration revenue
Revenue from Related Parties
General and Administrative Expense
General and Administrative Expense [Member]
Common stock shares held collateral for debt
Common Stock Shares Held Collateral For Debt
Number of shares pledged to secure a debt.
Other liabilities
Other Liabilities
Other Liabilities, Total
Unbilled accounts receivable, Additions
Contract With Customer Assets Additions
Contract with customer assets, additions.
Exercisable at December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Restricted cash
Restricted Cash
Restricted Cash, Total
Series B [Member]
Series B Preferred Stock [Member]
Schedule of Common Stock Reserved for Future Issuance
Schedule of Conversions of Stock [Table Text Block]
Regulatory and commercial milestone payments received
Regulatory And Commercial Milestone Payments Received
Regulatory and Commercial Milestone Payments Received.
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Accounts receivable, Beginning Balance
Accounts receivable, Ending Balance
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Revenue recognized included in the opening contract liabilities balance
Contract with Customer, Liability, Revenue Recognized
Schedule Of Related Party Transactions By Related Party [Table]
Schedule of Related Party Transactions, by Related Party [Table]
Other
Other Liabilities, Current
Other Liabilities, Current, Total
City Area Code
City Area Code
Deferred revenue, current and long-term, Deductions
Contract With Customer Liability Deductions
Contract with customer liability, deductions.
Capitalized Contract Cost, Net, Current
Contract assets ($0 and $250 from related party, respectively)
Other receivables
Other Receivables
Total
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Estimated Fair Value of Stock Options on the Grant Date Using Black-Scholes Option-Pricing Model
Patent cost reimbursements.
Patent cost reimbursements
Patent Cost Reimbursements
Total deferred tax assets
Deferred Tax Assets, Gross
Convertible preferred stock, par value
Temporary Equity, Par or Stated Value Per Share
Net deferred tax assets
Deferred Tax Assets, Net of Valuation Allowance
Deferred tax liabilities
Deferred Income Tax Liabilities, Net
Deferred Income Tax Liabilities, Net, Total
Other
Other Prepaid Expense, Current
Monthly base rent
Monthly Rent Expense
Monthly rent expense
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Abstract]
Contract with Customer, Liability
Contract with Customer, Liability, Total
Deferred revenue, current and long-term, Beginning Balance
Deferred revenue, current and long-term, Ending Balance
COMMITMENTS AND CONTINGENCIES (Note 9)
Commitments and Contingencies
Depreciation and amortization expense related to property and equipment
Accumulated Depreciation, Depletion and Amortization, Reclassifications from Property, Plant and Equipment
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Success payment liability assumptions term
Success Payment Liability Assumptions Term
Success payment liability assumptions term
Common stock issued to underwriters
Common Stock Issued To Underwriters
Common Stock Issued To Underwriters
Issuance of common stock upon initial public offering, net of issuance costs of $28.6 million (in shares)
Common stock shares issued
Stock Issued During Period, Shares, New Issues
Sublicensing expenses
Sublicensing Expenses
Sublicensing expenses.
Net unrealized loss on available-for-sale marketable securities
Marketable Securities, Unrealized Gain (Loss)
Marketable Securities, Unrealized Gain (Loss), Total
Proceeds from issuance of Series C convertible preferred stock, net of issuance costs
Proceeds from Issuance of Convertible Preferred Stock
Gross proceeds from issuance
Preferred Stock, Liquidation Preference, Value
Revenue Benchmark
Revenue Benchmark [Member]
Liabilities:
Liabilities, Fair Value Disclosure [Abstract]
Liabilities fair value
Financial and Nonfinancial Liabilities, Fair Value Disclosure
CASH. CASH EQUIVALENTS, AND RESTRICTED CASH ON THE BALANCE SHEET
Cash and cash equivalents
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Beginning Balance
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Ending Balance
Related Party
Related Party [Domain]
Issuance of common stock to acquire in-process research and development, Value (see Note 4)
Stock Issued During Period, Value, Other
Conversion of convertible preferred stock into common stock
Stock Issued During Period, Value, Conversion of Convertible Securities
Income Statement [Abstract]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Other Nonoperating Income (Expense) [Abstract]
Other income (expense):
Percentage of proceeds from loan
Limit Of Loans Payroll Costs Rate
Limit of loans payroll costs rate.
Net cash provided by (used in) investing activities
Net Cash Provided by (Used in) Investing Activities
Paycheck Protection Program Loan
Debt Disclosure [Text Block]
Purchases of property and equipment unpaid at period end
Capital Expenditures Incurred but Not yet Paid
Tax Credit Carryforward [Axis]
Unaudited Quarterly Results
Quarterly Financial Information [Text Block]
Commitment And Contingencies [Line Items]
Commitment And Contingencies [Line Items]
Commitment and Contingencies
Non-cash consideration in exchange for licensing and collaboration revenue
Non Cash Investing And Financing Activities Consideration In Exchange For Licensing And Collaboration Revenue
Non cash investing and financing activities consideration in exchange for licensing and collaboration revenue.
Tax Credit Carryforward, Name [Domain]
The Regents of the University of California/University of Vienna
The Regents Of University Of California University Of Vienna [Member]
The regents of the university of california/university of vienna.
Accrued personnel-related expenses
Employee-related Liabilities, Current
Employee-related Liabilities, Current, Total
General and administrative
General and Administrative Expense
General and Administrative Expense, Total
Property and equipment - net
Property and equipment, net
Property, Plant and Equipment, Net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Shares Available to Grant
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant [Abstract]
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant [Abstract]
Common stock, shares issued
Common Stock, Shares, Issued
Common Stock, Shares, Issued, Total
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current [Abstract]
NON-CURRENT ASSETS
Fair value at issuance
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Inputs Reconciliation, Issues
Repayment of promissory note
Proceeds from (Repayments of) Notes Payable
Proceeds from (Repayments of) Notes Payable, Total
Deferred rent and lease incentive liability
Deferred Rent Credit, Noncurrent
Total deferred tax liabilities
Total deferred tax liabilities
Deferred Tax Liabilities, Gross
Tenant improvement allowance
Payments for (Proceeds from) Tenant Allowance
Amortized Cost Basis
Debt Securities, Available-for-sale, Amortized Cost
Debt Securities, Available-for-sale, Amortized Cost, Total
Customer Concentration Risk [Member]
Security Exchange Name
Security Exchange Name
Statistical Measurement
Statistical Measurement [Domain]
Furniture and Equipment [Member]
Furniture and Fixtures [Member]
Measurement Input, Price Volatility [Member]
Expected Volatility
Subsequent Event Type [Domain]
Debt Disclosure [Abstract]
Other receivables
Increase (Decrease) in Other Receivables
Document Period End Date
Document Period End Date
Income Statement Location
Income Statement Location [Axis]
Accrued expenses and other current liabilities
Accrued Liabilities, Current
Accrued Liabilities, Current, Total
Line of Credit Facility, Lender
Line of Credit Facility, Lender [Domain]
Payment for participation
Related Party Transaction, Expenses from Transactions with Related Party
Common stock, shares authorized
Common Stock, Shares Authorized
Schedule of Unrecognized Tax Benefits
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Investments in equity securities
Investments in equity securities
Deferred Tax Liabilities, Investment in Noncontrolled Affiliates
Licensee E [Member]
Licensee E [Member]
Licensee E.
Use Of Estimates
Use of Estimates, Policy [Policy Text Block]
Contract assets:
Contract with Customer, Asset, after Allowance for Credit Loss, Current [Abstract]
Amortization of premiums on marketable securities
Accretion (Amortization) of Discounts and Premiums, Investments
Related Party
Related Party [Axis]
MSKCC success payments liability
Success Payment Liability
Success payment liability.
Thereafter
Lessee Operating Lease Liability Payments Due Year Four And Thereafter
Lessee operating lease liability payments due year four and thereafter
SUPPLEMENTAL CASH FLOW INFORMATION:
Supplemental Cash Flow Information [Abstract]
Balance Sheet Related Disclosures [Abstract]
Class of Stock
Class of Stock [Axis]
Cash based compensation
Cash based compensation
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Concentration Risk Benchmark
Concentration Risk Benchmark [Domain]
Antidilutive Securities
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
10x
Ten Times [Member]
Ten times.
Rest of World
Non-US [Member]
Stock-based compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-based Compensation Cost
Timing of Transfer of Good or Service
Timing of Transfer of Good or Service [Axis]
Debt instrument, maturity date
Debt Instrument, Maturity Date
Loss on disposal of property and equipment
Gain (Loss) on Disposition of Assets, Total
Gain (Loss) on Disposition of Assets
Effective income tax rate
Effective Income Tax Rate Reconciliation, Percent
Effective Income Tax Rate Reconciliation, Percent, Total
License I [Member]
License I [Member]
Entity Address, Address Line Two
Entity Address, Address Line Two
Current Fiscal Year End Date
Current Fiscal Year End Date
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Remaining performance obligation, expected timing of satisfaction, period
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period
Period for option
Period For Option
Period for option.
Grantee Status
Grantee Status [Axis]
Other assets
Increase (Decrease) in Other Operating Assets
Increase (Decrease) in Other Operating Assets, Total
Lease existence of option to renew term
Lessee, Operating Lease, Existence of Option to Extend [true false]
Revenue recognized, performance obligation, amount
Contract with Customer, Liability, Change in Timeframe, Performance Obligation Satisfied, Revenue Recognized
Line Of Credit Facility [Line Items]
Line of Credit Facility [Line Items]
Licensee F [Member]
Licensee F member.
Expenses incurred from transactions with related parties
Related Party Transaction, Selling, General and Administrative Expenses from Transactions with Related Party
Ownership percentage
Equity Method Investment, Ownership Percentage
Disaggregation Of Revenue [Table]
Disaggregation of Revenue [Table]
Change in fair value of MSKCC success payments liability
Change in fair value of the MSKCC success payments liability
Change in fair value of the MSKCC success payments liability
Change In Fair Value Of Success Payments Liability
Change in fair value of success payments liability.
Marketable securities, long-term
Marketable Securities, Noncurrent
Marketable Securities, Noncurrent, Total
ASSETS
Assets [Abstract]
Schedule of Prepaid Expenses and Other Current Assets
Schedule Of Prepaid Expenses And Other Current Assets Table [Text Block]
Schedule of prepaid expenses and other current assets.
Unrecognized tax benefits that would impact effective tax rate
Unrecognized Tax Benefits that Would Impact Effective Tax Rate
Conversion of convertible preferred stock into common stock (in shares)
Stock Issued During Period, Shares, Conversion of Convertible Securities
Assets:
Assets, Fair Value Disclosure [Abstract]
2022
Lessee, Operating Lease, Liability, to be Paid, Year One
Accounts Payable Current
Accounts Payable, Current
Accounts Payable, Current, Total
Accounts payable ($0 and $500 to related party, respectively)
Schedule of Subsidiary or Equity Method Investee [Table]
Debt instrument, face amount
Debt Instrument, Face Amount
Common stock, par value
Common Stock, Par or Stated Value Per Share
License and collaboration revenue
License And Collaboration Revenue
License and collaboration revenue.
Licensee D, Related Party [Member]
Licensee D, Related Party [Member]
Licensee D, related party.
Web Bank
Web Bank [Member]
Web bank.
Schedule of Benefit from Income Taxes
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Issuance of common stock to acquire in-process research and development, Shares (see Note 4)
Stock Issued During Period, Shares, Other
R&D tax credits, net of reserves
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Increases related to current year tax positions
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
State
State and Local Jurisdiction [Member]
Beginning Balance (in shares)
Ending Balance (in shares)
Shares, Outstanding
Sales Milestones
Sales Milestones [Member]
Sales milestones.
Total current income tax (benefit) expense
Current Income Tax Expense (Benefit)
Licensee C [Member]
Licensee C Member.
Research and Development Expenses and Accrued Liabilities
Research and Development Expense, Policy [Policy Text Block]
Fair Value by Liability Class
Fair Value by Liability Class [Domain]
Schedule of Fair Value and Amortized Cost of Cash Equivalents and Available-for-Sale Marketable Securities
Cash, Cash Equivalents and Investments [Table Text Block]
Other comprehensive loss:
Other Comprehensive Income (Loss), Tax [Abstract]
Net loss before provision for (benefit from) income taxes
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Document Type
Document Type
Maximum value of success payments and control payment
Maximum Limited Value Of Success Payments And Control Payment
Maximum limited value of success payments and control payment.
Increase decrease in fair value of success payments liability.
Increase decrease in fair value of success payments liability
Increase Decrease In Fair Value Of Success Payments Liability
Federal
Domestic Tax Authority [Member]
Stock Based Compensation Vesting Cliff Period.
Stock Based Compensation Vesting Cliff Period
Vesting cliff period
Preferred stock, par value $0.0001 per share, 10,000,000 and no shares authorized at December 31, 2021 and 2020, respectively; no shares issued and outstanding as of December 31, 2021 and 2020, respectively.
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Total
Summary of Accrued Expenses and Other Current Liabilities
Schedule of Accrued Liabilities [Table Text Block]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Summary of Amounts of Success Payments MSKCC
Success Payments Table [Text Block]
Success payments.
Total current assets
Assets, Current
Liability Class
Liability Class [Axis]
Disaggregation Of Revenue [Line Items]
Disaggregation of Revenue [Line Items]
Employee [Member]
Share-based Payment Arrangement, Employee [Member]
Stock-Based Compensation Expense
Share-based Payment Arrangement [Policy Text Block]
Incentive stock options.
Incentive Stock Options [Member]
Incentive Stock Options
Contract Assets
Commodity Contract Asset, Current
Contract assets related party
Stock Options
Stock Options, Authorized for Future Issuance
Share-based Payment Arrangement, Option [Member]
Aggregate Intrinsic Value
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Aggregate Intrinsic Value [Abstract]
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Aggregate Intrinsic Value [Abstract]
Federal
Deferred Federal Income Tax Expense (Benefit)
Outstanding
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Provision for (benefit from) income taxes
Total income tax (benefit) expense
Benefit from income taxes
Income Tax Expense (Benefit)
Benefit from income taxes
Deferred revenue, current and long-term
Increase (Decrease) in Deferred Revenue
Net loss per share, basic and diluted
Net loss per share, basic and diluted
Earnings Per Share, Basic and Diluted
Common Stock
Common Stock [Text Block]
Common stock text block.
Prepaid directors' and officers' insurance
Prepaid Insurance
Vested and expected to vest at December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Patent Costs
Patent Costs [Policy Text Block]
Disclosure of accounting policy for patent costs.
Common Stock Shares Outstanding
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
State
Current State and Local Tax Expense (Benefit)
Preferred stock, par value
Preferred Stock, No Par Value
Plan Name
Plan Name [Axis]
Loan, term
Debt Instrument, Term
Debt instrument, Term
Less: accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Revenue Recognition
Revenue [Policy Text Block]
Cash and Cash Equivalents [Domain]
Total deferred income tax (benefit) expense
Deferred Income Tax Expense (Benefit)
Total operating expenses
Operating Expenses
IPO [Member]
IPO
Offering price per share
Offering Price Per Share
Offering Price Per Share
Common stock issued in IPO, net of issuance costs
Increase in additional paid-in capital
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Preferred Stock, Issued and Outstanding
Preferred Stock [Member]
Outstanding, Beginning Balance
Outstanding, Ending Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price
CASH FLOWS FROM OPERATING ACTIVITIES:
Net Cash Provided by (Used in) Operating Activities [Abstract]
Issuance of common stock to acquire in-process research and development (Note 4)
Research and Development in Process
Acquired in-process research and development accrued
Deferred income taxes:
Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract]
Estimated Fair Value
Available For Sale Securities Estimated Fair Value
Available for sale securities estimated fair value.
Summary of Future Minimum Lease Payment Under Leases
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Earnings Per Share [Abstract]
Stock option plan description
Share-based Compensation Arrangement by Share-based Payment Award, Description
2023
Lessee, Operating Lease, Liability, to be Paid, Year Two
Carrying value of investment
carrying value of investment
carrying value of investment
Net loss
Net loss and comprehensive loss
Net Income (Loss) Attributable to Parent
Concentration Risk [Line Items]
Concentration Risk [Line Items]
Schedule of Reconciliation of Statutory Income Tax Rate to Our Effective Tax Rate
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
NOL and tax attributes
Deferred Tax Assets Operating Loss Carryforwards And Tax Attributes Carryforwards
Deferred tax assets operating loss carryforwards and tax attributes carryforwards.
Weighted-Average Remaining Contractual Term of Shares Exercisable (years)
Share-based Payment Arrangement, Option, Exercise Price Range, Exercisable, Weighted Average Remaining Contractual Term
Concentration of Credit Risk and Other Uncertainties
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Laboratory and Office Space
Laboratory and Office Space [Member]
Laboratory and office space.
Research and Development Expense
Research and Development Expense [Member]
Document Fiscal Period Focus
Document Fiscal Period Focus
Issuance of Series C convertible preferred stock, net of issuance costs of $6.2 million
Temporary Equity, Stock Issued During Period, Value, New Issues
Accounting Policies [Abstract]
Reduction in general and administrative expenses
Reduction Of General And Administrative Expenses
Reduction of general and administrative expenses.
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Other Income
Other Income
Entity Address Address Line1
Entity Address, Address Line One
Outstanding, Beginning Balance
Outstanding, Ending Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number
Exercise Prices Range 4
Exercise Prices Range 4 [Member]
Exercise Prices Range 4.
Total current liabilities
Liabilities, Current
Regulatory Milestones
Regulatory Milestones [Member]
Regulatory milestones.
Net loss
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Commercial Paper
Commercial Paper [Member]
Entity Address Postal Zip Code
Entity Address, Postal Zip Code
Contract with Customer, Asset, after Allowance for Credit Loss, Current
Contract with Customer, Asset, after Allowance for Credit Loss, Current, Total
Unbilled accounts receivable, Beginning Balance
Unbilled accounts receivable, Ending Balance
Common Shares Subject to Nonrecourse Notes
Common Shares Subject To Nonrecourse Notes [Member]
Common shares subject to nonrecourse notes
Equity Multiple
Equity Multiple [Domain]
Equity multiple.
Outstanding
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value
Future minimum lease payment
Total
Lessee, Operating Lease, Liability, to be Paid
Subsequent Event [Table]
Licensee B [Member]
Licensee B [Member]
Licensee B.
Future development, regulatory, and product launch milestones payment received
Future Development Regulatory And Product Launch Milestones Payment Received
Future development, regulatory, and product launch milestones payment received.
Product and Service
Product and Service [Domain]
Total
Accrued Liabilities and Other Liabilities
Temporary Equity, Beginning Balance
Temporary Equity, Ending Balance
Temporary Equity, Carrying Amount, Attributable to Parent
Carrying Value
Change in fair value of equity securities
Change in fair value of equity securities
Equity Securities, FV-NI, Gain (Loss)
Equity Securities, FV-NI, Gain (Loss), Total
Revenues
Revenues
Revenues, Total
Proceeds from initial public offering of common stock, net of offering costs
Proceeds from initial public offering, gross
Proceeds from Issuance Initial Public Offering
Convertible Preferred Stock
Convertible Preferred Stock [Member]
Convertible Preferred Stock [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Net cash used in operating activities
Cash generated in operating activities
Net Cash Provided by (Used in) Operating Activities
CASH AND CASH EQUIVALENTS —Beginning of period
CASH AND CASH EQUIVALENTS —End of period
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Stock Options, Issued and Outstanding
Equity Option [Member]
Equity Components
Equity Components [Axis]
CURRENT ASSETS:
Assets, Current [Abstract]
Restricted Cash and Cash Equivalents, Current
Restricted Cash and Cash Equivalents, Current, Total
Restricted Cash
Entity Registrant Name
Entity Registrant Name
Other
Other Receivables, Net, Current
Other Receivables, Net, Current, Total
Common stock outstanding percentage
Common stock outstanding percentage
Series A [Member]
Series A Preferred Stock [Member]
Purchase of shares.
Purchase of shares
Purchase of additional shares
Decrease in regulatory milestone
Decrease In Regulatory Milestone
Decrease in regulatory milestone.
Reimbursement Expense
Reimbursement Expense
Entity Interactive Data Current
Entity Interactive Data Current
Contract liabilities:
Contract with Customer, Liability [Abstract]
Entity Address City Or Town
Entity Address, City or Town
Customer [Axis]
Probability
Measurement Input Probability [Member]
Measurement input probability member.
Indefinite-lived Intangible Assets, Major Class Name
Indefinite-lived Intangible Assets, Major Class Name [Domain]
State income taxes
Deferred Tax Assets, State Taxes
Accounts Receivable
Accounts Receivable [Member]
Measurement Input, Expected Term [Member]
Expected Term (Years)
Current income taxes
Current Federal, State and Local, Tax Expense (Benefit) [Abstract]
Unusual or Infrequent Item, or Both
Unusual or Infrequent Item, or Both [Domain]
Balance Sheet Items
Supplemental Balance Sheet Disclosures [Text Block]
Revenue Not from Contract with Customer
Revenue from related party
Expected term (in years)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term
Trading Symbol
Trading Symbol
Lessor operating lease description
Lessor, Operating Lease, Description
Credit card liability
Line of Credit, Current
Schedule of Assumptions Used in Valuation of MSKCC Success Payments Liability
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Organization Consolidation And Presentation Of Financial Statements Line Items.
CASH FLOWS FROM INVESTING ACTIVITIES:
Net Cash Provided by (Used in) Investing Activities [Abstract]
Patent costs gross
Patent Costs Gross
Patent costs gross.
Concentration Risk Type [Axis]
Revenue from Rights Concentration Risk [Member]
Upfront payment fee
Upfront Payment Fee
Upfront payment fee.
Noncash Investing And Financing Activities Deferred Issuance Costs Related To I P O
Noncash investing and financing activities deferred issuance costs related to IPO.
Deferred issuance costs related to initial public offering accrued
Local Phone Number
Local Phone Number
Total stockholders' equity (deficit)
Beginning Balance
Ending Balance
Stockholders' Equity Attributable to Parent
Subsequent Event Type [Axis]
Transferred at Point in Time [Member]
Point in Time
Weighted-Average Exercise Price
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Summary of results of operations quarterly basis
Quarterly Financial Information [Table Text Block]
Unrecognized Tax Benefits
Unrecognized Tax Benefits, Ending Balance
Unrecognized Tax Benefits, Beginning Balance
Change in fair value
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Inputs Reconciliation, Period Increase (Decrease)
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Inputs Reconciliation, Period Increase (Decrease), Total
New Accounting Pronouncements Not Yet Adopted
New Accounting Pronouncements Not Yet Adopted Policy Policy [Text Block]
Disclosure of accounting policy pertaining to new accounting pronouncements not yet adopted.
2022
Operating lease payments
Operating Lease, Payments
Comprehensive Loss
Comprehensive Income, Policy [Policy Text Block]
Preferred stock, shares issued
Preferred Stock, Shares Issued
Preferred Stock, Shares Issued, Total
Memorial Sloan Kettering Cancer Center
M S K C C Agreement [Member]
MSKCC Agreement.
Licensee G, Related Party [Member]
Licensee G, related party member
Assets fair value
Assets, Fair Value Disclosure
Statistical Measurement
Statistical Measurement [Axis]
Entity Small Business
Entity Small Business
Deferred revenue, recognized
Deferred Revenue, Revenue Recognized
Other liabilities
Increase (Decrease) in Other Operating Liabilities
Increase (Decrease) in Other Operating Liabilities, Total
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Leases
Lessee, Leases [Policy Text Block]
Conversion of convertible preferred stock to common stock at closing of initial public offering
Conversion of Convertible Preferred Stock to Common Stock at Closing of Initial Public Offering
Conversion of Convertible Preferred Stock to Common Stock at Closing of Initial Public Offering
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period
Options cancelled or forfeited
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Total
Share price
Share Price
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Stock-based compensation expense
APIC, Share-based Payment Arrangement, Increase for Cost Recognition
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Credit Facility
Credit Facility [Axis]
Schedule of Components of Deferred Tax Assets and Liabilities
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Impairment of Long-Lived Assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Research Tax Credit Carryforward [Member]
Deferred revenue, net of current portion
Deferred Revenue, Current
Deferred Revenue, Current, Total
Increase of unbilled accounts receivable
Contract with Customer, Asset, Increase (Decrease) for Contract Acquired in Business Combination
Estimated useful lives of assets
Property, Plant and Equipment, Useful Life
Balance Sheet Location
Balance Sheet Location [Axis]
Defined contribution plan, Employer matching contribution percent of match
Defined Contribution Plan, Employer Matching Contribution, Percent of Match
Fair Value Measurements
Fair Value Measurement, Policy [Policy Text Block]
Marketable Securities, Short-Term [Member]
Marketable Securities, Short-Term [Member]
Marketable securities, short-term
Additional paid-in-capital
Additional Paid in Capital
Additional Paid in Capital, Total
Additional Paid in Capital, Beginning Balance
Additional Paid in Capital, Ending Balance
401(K) Savings plan
Defined Contribution Plan [Text Block]
Compensation for Participating
Related Party Transaction, Amounts of Transaction
Dr. Jennifer A. Doudna
Dr Jennifer A Doudna [Member]
Dr. Jennifer A. Doudna.
Upfront option payment
Upfront Option Payment
Upfront option payment received.
Schedule of Financial Instruments Measured on Recurring Basis
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Numerator
Net Income (Loss) Attributable to Parent [Abstract]
Options granted
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Non-Employee [Member]
Share-based Payment Arrangement, Nonemployee [Member]
Net operating loss carryforwards stock ownership percentage
Net Operating Loss Carryforwards Stock Ownership Percentage
Net operating loss carryforwards stock ownership percentage.
Proceeds from Other Debt
Proceeds from PPP Loan
Sale of Stock
Sale of Stock [Domain]
Convertible preferred stock, shares issued
Temporary Equity, Shares Issued
Unusual or Infrequent Item, or Both
Unusual or Infrequent Item, or Both [Axis]
Equity [Abstract]
Proceeds from sale of property and equipment
Proceeds from Sale of Property, Plant, and Equipment, Total
Proceeds from Sale of Property, Plant, and Equipment
Proceeds from initial public offering, net
Proceeds From Issuance Initial Public Offering Net
Proceeds from Issuance Initial Public Offering, net.
Success payment liability assumption
Alternative Investment
Extinguishment of PPP Loan and accrued interest
Extinguishment of Debt Amount and Accrued Interest
Extinguishment of debt amount and accrued interest.
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Revenue from Contract with Customer [Abstract]
Plan Name
Plan Name [Domain]
AbbVie Agreement
Abb Vie Agreement [Member]
AbbVie Agreement.
Temporary Equity, by Class of Stock [Table]
Class of Stock [Line Items]
Class of Stock [Line Items]
Deferred tax assets
Components of Deferred Tax Assets [Abstract]
Lender Name
Lender Name [Axis]
Income Tax Authority [Axis]
CARES Act
C A R E S Act [Member]
CARES Act.
M S K C C Success Payments Liability [Member]
MSKCC Success Payments Liability [Member]
MSKCC Success Payments Liability
State taxes, net of federal benefit
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Issuance of common stock upon initial public offering, net of issuance costs of $28.6 million
Stock Issued During Period, Value, New Issues
Accrued liabilities
Accrued Liabilities, Total
Accrued Liabilities
Options exercised
Share Based Compensation Arrangement By Share Based Payment Award Options Exercised In Period Weighted Average Remaining Contractual Term
Weighted average remaining contractual term for option awards exercised during period.
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]
Exercise Prices Range 1
Exercise Prices Range 1 [Member]
Exercise prices range 1 [Member]
Quarterly Financial Information Disclosure [Abstract]
Interest expense
Interest Expense
Interest Expense, Total
Employee Stock Purchase Plan 2021
Employee Stock Purchase Plan Two Thousand Twenty One [Member]
Employee Stock Purchase Plan Two Thousand Twenty One [Member]
Cash Equivalents, at Carrying Value
Cash Equivalents, at Carrying Value, Total
Stock-based compensation
Share-based Payment Arrangement, Noncash Expense, Total
Share-based Payment Arrangement, Noncash Expense
Total
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Schedule of Stock Option Activity
Share-based Payment Arrangement, Option, Activity [Table Text Block]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Related Party Transactions [Abstract]
U.S. treasury bills.
U.S. Treasury Bills [Member]
U.S. Treasury Bills [Member]
Loans Payable, Noncurrent
Loans Payable, Noncurrent, Total
Promissory note - PPP Loan, net of current portion
Payment annual escalation
Annual Escalation Of Rent
Annual escalation of rent
Options cancelled or forfeited
Weighted Average Remaining Contractual Term Options Cancelled or Forfeited
Share based Compensation weighted average remaining contractual term options cancelled or forfeited.
Lease initial term
Lessor, Operating Lease, Term of Contract
Federal
Current Federal Tax Expense (Benefit)
Retroactive adjustment to beginning retained earnings for Adoption of ASC 606
Retroactive Adjustment to Beginning Retained Earnings For Adoption of 606
Retroactive Adjustment to Beginning Retained Earnings For Adoption of 606
Other
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Deferred rent and lease incentive liability
Increase Decrease In Deferred Rent And Lease Incentive Liability
Increase decrease in deferred rent and lease incentive liability.
Exercise price as percentage of fair market value, Maximum
Share Based Compensation Arrangement By Share Based Payment Award Exercise Price As Percentage Of Fair Market Value Maximum
Share based compensation arrangement by share Based payment award exercise price as percentage of fair market value maximum.
Temporary Equity [Table Text Block]
Schedule of Convertible Preferred Stock and Liquidation Preference
Success payment liability assumption
Alternative Investment, Measurement Input
Exercisable at December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number
Net cash provided by financing activities
Net Cash Provided by (Used in) Financing Activities
Commitments and Contingencies Disclosure [Abstract]
Common Stock, Number of Shares, Par Value and Other Disclosures [Abstract]
Extinguishment of PPP Loan and accrued interest
Extinguishment of Debt, Gain (Loss), Net of Tax
Extinguishment of Debt, Gain (Loss), Net of Tax, Total
Deferred issuance cost
Debt Issuance Costs, Net
Debt Issuance Costs, Net, Total
TOTAL ASSETS
Assets
Level 2
Fair Value, Inputs, Level 2 [Member]
2017 Plan
Two Thousand Seventeen Plan [Member]
Two Thousand Seventeen Plan [Member]
Fair value of convertible preferred stock
Equity Issued in Business Combination, Fair Value Disclosure
Options exercised
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period
Issuance of common stock on exercise of stock options (in shares)
Unrecognized tax benefits, income tax penalties and interest accrued
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued, Total
Type Of Revenue Extensible List
Revenue, Product and Service [Extensible Enumeration]
Operating Leases Lease Space
Operating leases lease space.
Statement [Line Items]
Statement [Line Items]
TOTAL LIABILITIES, CONVERTIBLE PREFERRED STOCK, AND STOCKHOLDERS' EQUITY (DEFICIT)
Liabilities and Equity
Change in fair value of other income (expense)
Change In Fair Value Of Other Income(Expense)
Change in fair value of other income(expense)
Balance Sheet Location
Balance Sheet Location [Domain]
Dividends
Dividends
Dividends, Total
Statement of Cash Flows [Abstract]
Additional Paid-In Capital
Additional Paid-in Capital [Member]
Capital lease financing for purchase of assets
Capital Lease Financing For Purchase Of Assets
Capital lease financing for purchase of assets
Security12b Title
Title of 12(b) Security
Net comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Options cancelled or forfeited
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Addition Due To Options Forfeitures And Cancelled In Period
Share-based compensation arrangement by share-based payment award, reduction in the number of shares available for grant due to options forfeitures and cancelled in period.
Deferred revenue, current and long-term, Additions
Contract With Customer Liability Additions
Contract with customer liability, additions.
Interest Income, Other
Interest income
Level 3
Fair Value, Inputs, Level 3 [Member]
Accrued sublicensing fees
Accrued Sublicensing Fees
Accrued sublicensing fees.
Exercisable at September 30, 2021
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Exercisable Number
Share-based compensation arrangement by share-based payment award, number of shares available for grant, exercisable number.
Quarterly Financial Data [Abstract]
Aggregate success payment
Aggregate Success Payment
Aggregate success payment.
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Prepaid Rent
Prepaid rent
Award Type
Award Type [Domain]
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage
Option vesting percentage
Series A-1 [Member]
Series A-1 preferred stock.
Series A1 Preferred Stock [Member]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Stock option expiration period
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period
Schedule of Property and Equipment
Property, Plant and Equipment [Table Text Block]
Fair value of success payments liability
Fair Value Of Success Payments Liability
Fair value of Success payments liability.
Level 1
Fair Value, Inputs, Level 1 [Member]
2025
Lessee, Operating Lease, Liability, to be Paid, Year Four
Debt instrument, interest rate
Debt Instrument, Interest Rate, Stated Percentage
Net deferred tax assets (liabilities)
Deferred Tax Assets, Net
Deferred Tax Assets, Net, Total
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Lab Equipment [Member]
Laboratory Equipment [Member]
Laboratory equipment.
Restricted Stock Awards
Restricted Stock [Member]
Total other income (expense)
Nonoperating Income (Expense)
Corporate Debt Securities
Corporate Debt Securities [Member]
Vested and expected to vest at December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Temporary Equity, Liquidation Preference
Temporary Equity, Liquidation Preference
Options granted
Stock options granted during period
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross
Entity Current Reporting Status
Entity Current Reporting Status
Revenue
Revenue from Contract with Customer [Text Block]
Series B Convertible Preferred Stock
Series B Convertible Preferred Stock [Member]
Series B convertible preferred stock.
Purchases of marketable securities
Purchases of marketable securities
Payments to Acquire Marketable Securities
Payments to Acquire Marketable Securities, Total
Remaining performance obligations
Transaction price allocated to the remaining performance obligations
Revenue, Remaining Performance Obligation, Amount
SUPPLEMENTAL SCHEDULE OF NON-CASH INVESTING AND FINANCING ACTIVITES:
Noncash Investing and Financing Items [Abstract]
Measurement Input Type
Measurement Input Type [Domain]
Entity Voluntary Filers
Entity Voluntary Filers
State net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, State and Local
Other Income
Other Income [Policy Text Block]
Disclosure of accounting policy for other income.
Money Market Funds [Member]
Money Market Investments (Included in Cash and Cash Equivalents)
Retirement Plan Name
Retirement Plan Name [Axis]
Operating Leases, Future Minimum Payments Due, Future Minimum Sublease Rentals
Future minimum lease payments related to capital lease
Increase in unbilled accounts receivable
Contract assets
Increase (Decrease) in Contract with Customer, Asset
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Decreases related to lapse of statutes
Unrecognized Tax Benefits, Reduction Resulting from Lapse of Applicable Statute of Limitations
Lease option to renew term description
Lessee, Operating Lease, Option to Extend
Debt Securities, Available-for-sale [Table]
Transferred over Time [Member]
Over Time
Options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Remaining Contractual Term
Weighted average remaining contractual term for option awards granted during period.
Net Loss Per Share
Earnings Per Share, Policy [Policy Text Block]
Schedule of Stock-Based Compensation Expenses Recorded in the Condensed Consolidated Statements of Operations and Comprehensive Loss
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Significant Agreements
Significant Agreements [Text Block]
Significant agreements.
Lessee operating lease remainder of the lease term
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
Retirement Benefits [Abstract]
Computer Equipment [Member]
Computer Equipment [Member]
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Abstract]
State
Deferred State and Local Income Tax Expense (Benefit)
Other Comprehensive Income (Loss)
AOCI Attributable to Parent [Member]
Initial fair value of MSKCC success payments liability
Fair Value Of Success Payment Liability
fair value of success payment liability.
Auditor Firm Id
Auditor Firm ID
Deferred financing costs
Deferred Costs, Current
Deferred Costs, Current, Total
Milestone revenue.
Milestone Revenue
Income Statement Location
Income Statement Location [Domain]
United States
UNITED STATES
Auditor Name
Auditor Name
Reimbursement percentage
Percent Rate Of Reimbursement
Percent rate of reimbursement.
Balance at December 31, 2021
Balance at December 31, 2020
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis with Unobservable Inputs
Preferred stock, shares authorized
Preferred Stock, Shares Authorized
Other Assets [Member]
Other Assets [Member]
Exercisable at December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Accrued expenses and other current liabilities
Increase (Decrease) in Accrued Liabilities
Increase (Decrease) in Accrued Liabilities, Total
Minimum
Minimum [Member]
Payments to acquire in-process research and development
Payments to Acquire in Process Research and Development
Measurement Input Fair Value Of Common Stock [Member]
Measurement input fair value of common stock member.
Fair Value of Common Stock
Vested and expected to vest at December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Measurement Frequency
Measurement Frequency [Domain]
Security deposit
Security Deposit
Issuance of common stock on exercise of options
Stock Issued During Period, Value, Stock Options Exercised
Potential future milestone payments
Future Milestone Payments
Future milestone payments.
Capital Lease Obligations
Capital Lease Obligations, Total
Capital lease obligation
Measurement Input, Risk Free Interest Rate [Member]
Risk Free Interest Rate
Timing of Transfer of Good or Service
Timing of Transfer of Good or Service [Domain]
Document Annual Report
Valuation Allowance
Deferred Tax Assets, Valuation Allowance
Valuation Allowance, Total
Deferred Tax Assets, Valuation Allowance
Payment for licensing revenue
Payment for Licensing Revenue
Payment for licensing revenue.
Ginkgo License Agreement
Ginkgo License Agreement [Member]
Ginkgo license agreement.
Exercise Price Range [Axis]
Share Granted
Shares Granted, Value, Share-based Payment Arrangement, after Forfeiture
Shares Granted, Value, Share-based Payment Arrangement, after Forfeiture, Total
Schedule Of Defined Benefit Plans Disclosures [Table]
Schedule of Defined Benefit Plans Disclosures [Table]
CASH FLOWS FROM FINANCING ACTIVITIES:
Net Cash Provided by (Used in) Financing Activities [Abstract]
Pre-tax book income (loss) in the United States
Income (Loss) from Continuing Operations before Income Taxes, Domestic
Entity Filer Category
Entity Filer Category
Income Taxes
Income Tax, Policy [Policy Text Block]
Patent prosecution and maintenance costs
Patent prosecution and maintenance costs
Patent prosecution and maintenance costs.
Document Fiscal Year Focus
Document Fiscal Year Focus
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Vested and expected to vest at December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Deferred Issuance Costs
Deferred Issuance Costs [Policy Text Block]
Deferred Issuance Costs [Policy Text Block]
Investments in Equity Securities
Equity Method Investments [Policy Text Block]
Construction in Progress [Member]
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Income Taxes
Income Tax Disclosure [Text Block]
Notes and Loans Payable
Notes and Loans Payable, Total
Promissory note - PPP Loan
Entity Ex Transition Period
Entity Ex Transition Period
Accounts Payable, Related Parties, Current
Accounts payable related parties, Current
Fair Value Disclosures [Abstract]
Prepaid income taxes
Prepaid Taxes
Shares Exercisable
Share-based Payment Arrangement, Option, Exercise Price Range, Shares Exercisable
Share-based Payment Arrangement, Option, Exercise Price Range, Shares Exercisable, Ending Balance
Share-based Payment Arrangement, Option, Exercise Price Range, Shares Exercisable, Beginning Balance
Major customers.
Major Customers [Member]
Total
Accounts receivable, Additions
Accounts Receivable Additions
Accounts receivable additions.
Maximum
Maximum [Member]
Schedule of Changes in Company's Contract Assets and Liabilities
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]
Accrued research and development expenses
Accrued Research And Development Expenses
Accrued research and development expenses.
Entity Central Index Key
Entity Central Index Key
5x
Five Times [Member]
Five times.
Restricted Cash
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Commercial milestones
Commercial Milestones
Commercial milestones.
Measurement Input Type
Measurement Input Type [Axis]
Intellia Therapeutics, Inc.
Intellia Therapeutics Inc [Member]
Intellia Therapeutics, Inc.
Rent expense
Operating Lease, Expense
Temporary Equity [Line Items]
Exercise Prices Range 3
Exercise Prices Range 3 [Member]
Exercise Prices Range 3.
Future contingent milestone payments
Future Contingent Milestone Payments
Future contingent milestone payments.
Cash and Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Potential milestone payment
Revenue Recognition Milestone Method Pending
Revenue recognition milestone method pending.
Temporary Equity Disclosure [Abstract]
Entity Tax Identification Number
Entity Tax Identification Number
Equity Component
Equity Component [Domain]
Preferred stock, par value
Preferred Stock, Par or Stated Value Per Share
Marketable securities other than temporary impairment loss
Marketable Securities, Gain (Loss), Excluding Other-than-temporary Impairment Loss
Marketable Securities, Gain (Loss), Excluding Other-than-temporary Impairment Loss, Total
DuPont
Du Pont [Member]
DuPont.
Volatility
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Loss on extinguishment of PPP Loan
Gain on extinguishment of PPP Loan
Gain (Loss) on Extinguishment of Debt
Gain (Loss) on Extinguishment of Debt, Total
Licensee A [Member]
Licensee A [Member]
Licensee A
Property and Equipment
Property, Plant and Equipment, Policy [Policy Text Block]
Forward stock split, conversion ratio
Stockholders' Equity Note, Stock Split, Conversion Ratio
common stock ratio
Research collaboration agreement, period
Research Collaboration Agreement Period
Research collaboration agreement period.
Payments
Related Party Costs
Income Tax Authority [Domain]
Weighted-average period
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Emerging Growth Company
Emerging Growth Company [Policy Text Block]
Disclosure of accounting policy for emerging growth company.
Deferred tax liabilities:
Deferred Tax Liabilities, Gross [Abstract]
ESPP
Employee Stock Purchase Plan [Member]
Employee stock purchase plan member.
Accounts receivable
Increase (Decrease) in Accounts Receivable
Subsequent Events [Abstract]
Subsequent Event [Line Items]
Leasehold Improvements [Member]
Leasehold Improvements [Member]
Debt Securities, Available-for-sale [Abstract]
Total
Concentration Risk, Percentage
Statement [Table]
Statement [Table]
Cash Equivalents [Member]
Entity File Number
Entity File Number
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Allowance for doubtful accounts
Allowance for Credit Loss, Receivable, Other, Current
Retained Earnings (Accumulated Deficit)
Retained Earnings [Member]
Multiple of Initial Share Price giving rise to a success payment
Shares Issued, Price Per Share
Temporary equity, shares issued price per share
Licensing and collaboration revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Revenue
Payments of stock issuance costs
Payments of Stock Issuance Costs
Accounts payable
Increase (Decrease) in Accounts Payable
Increase (Decrease) in Accounts Payable, Total
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Federal net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Addition option pool
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Addition Of New Shares In Period
Share-based compensation arrangement by share-based payment award, addition of new shares in the number of shares available for grant during period.
Basis Of Presentation and Principles of Consolidations
Basis of Presentation and Significant Accounting Policies [Text Block]
CURRENT LIABILITIES:
Liabilities, Current [Abstract]
Equity Compensation Plans
Share-based Payment Arrangement [Text Block]
Subsequent Event [Member]
Subsequent Event
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Equity Multiple
Equity Multiple [Axis]
Equity multiple.
Convertible preferred stock, par value $0.0001 per share; no shares authorized, issued, and outstanding at December 31, 2021; 7,766,582 shares authorized, issued, and outstanding at December 31, 2020 (liquidation preference $41,620 at December 31, 2020)
Temporary Equity, Par Value
Common Stock
Common Stock [Member]
Property and equipment, gross
Property, Plant and Equipment, Gross
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
NOLs, deduction limit
Net Operating Loss Carryforwards Deduction Limit
Net operating loss carryforwards, deduction limit.
Percentage of eligible employee to purchase shares of common stock discount
Percentage of Eligible Employee to Purchase Shares of Common Stock Discount
Percentage of eligible employee to purchase shares of common stock discount.
Entity Public Float
Cover [Abstract]
Credit Facility
Credit Facility [Domain]
Acquisition of In-Process Research and Development Assets
In Process Research and Development, Policy [Policy Text Block]
Asset Class
Asset Class [Axis]
Deferred tax assets, tax credit carryforwards, research
Deferred Tax Assets, Tax Credit Carryforwards, Research
Convertible preferred stock, shares outstanding
Temporary Equity, Beginning Balance (in shares)
Temporary Equity, Ending Balance (in shares)
Temporary Equity, Shares Outstanding
Statement of Stockholders' Equity [Abstract]
Concentration Risk [Table]
Concentration Risk [Table]
Number of operating segment
Number of Operating Segments
Collaboration and License Agreement with AbbVie
Collaboration And License Agreement With Abb Vie [Member]
Collaboration and license agreement with AbbVie.
Voting interest
Variable Interest Entity, Qualitative or Quantitative Information, Ownership Percentage
Share-based Payment Arrangement [Abstract]
MSKCC Success Payments Liability
Success Payments Liability [Policy Text Block]
Success payments liability.
MSKCC Success payments (in millions)
Success Payment
Success payment.
Cash, cash equivalents and short term marketable securities
Cash, Cash Equivalents, and Short-term Investments
Cash, Cash Equivalents, and Short-term Investments, Total
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Document Transition Report
Document Transition Report
Weighted average grant date fair value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value
Proceeds from sale of equity securities
Proceeds From Sale Of Equity Securities
Proceeds from sale of equity securities.
Percentage of outstanding shares held by individual.
Percentage Of Outstanding Shares Held By Individual
Percentage of outstanding shares held by individual
Grantee Status
Grantee Status [Domain]
Proceeds from exercise of stock options
Proceeds from Stock Options Exercised
Options cancelled or forfeited
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
2012 Stock Option and Issuance Plan
Two Thousand And Twelve Stock Option And Issuance Plan [Member]
2012 Stock Option and Issuance Plan [Member]
Lease renewal term
Lessee, Operating Lease, Renewal Term
Capitalized license and patent costs
Deferred Tax Assets Tax Deferred Capitalized License and Patent Costs
Deferred tax assets tax deferred capitalized license and patent costs.
Research and development
Research and Development Expense
Research and Development Expense, Total
Debt Instrument, Maturity Date, Description
Debt instrument Term, Description
Convertible preferred stock issued
Stock Issued During Period, Shares, Acquisitions
Weighted-Average Remaining Contractual Term of Shares Outstanding (years)
Share-based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Remaining Contractual Term
Preferred Class A [Member]
Preferred Class A [Member]
Stock-based compensation expense
Stock-based compensation
Share-based Payment Arrangement, Expense
Patent cost reimbursements
Patent Reimbursements Expense
Patent Reimbursements Expense.
Concentration Risk Benchmark
Concentration Risk Benchmark [Axis]
Statement of Financial Position [Abstract]
Share-based Payment Arrangement, Option, Exercise Price Range [Line Items]
Expected dividend yield
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Upfront cash payment
Upfront Cash Payment Receivable Under Agreement
Upfront cash payment receivable under agreement.
Deferred revenue and expenses
Deferred Tax Assets, Tax Deferred Expense, Other
Payments on capital lease
Repayments of Long-term Capital Lease Obligations
Depreciation and amortization
Depreciation, Depletion and Amortization
Depreciation, Depletion and Amortization, Total
Accrued expenses and reserve
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Repayment of loan issued by stockholder, shares
Repayment Of Loan Issued by Stockholder, in shares
Repayment Of Loan Issued by Stockholder, in shares
Prepaid contract manufacturing and clinical costs
Prepaid contract manufacturing and clinical costs
Accounts receivable, Deductions
Accounts Receivable Deductions
Accounts receivable deductions
PPP Loan
P P P Loan [Member]
Paycheck protection program loan.
2026
Lessee, Operating Lease, Liability, to be Paid, Year Five
Federal income tax (benefit) at statutory rate
Federal income tax (benefit) at statutory rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
STOCKHOLDERS' EQUITY (DEFICIT)
Stockholders' Equity Attributable to Parent [Abstract]
Operating Loss Carryforward Indefinitely Member
Operating loss carryforward indefinitely member.
Unrealized Gains
Available For Sale Securities Unrealized Gain
Available for sale securities unrealized gain.
Description of the Business, Organization, and Liquidity
Nature of Operations [Text Block]
Decreases related to prior year tax positions
Decreases related to prior year tax positions
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Cash and Cash Equivalents [Axis]
15x
Fifteen Times [Member]
Fifteen times.
Deferred tax liabilities
Increase (Decrease) in Deferred Liabilities
Increase (Decrease) in Deferred Liabilities, Total
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Schedule of Change in Fair Value of Financial Liability
Investments in equity securities
Carrying value of investment
Equity Method Investments
Long term investments
Long-term Investments
Long-term Investments, Total
Basic and Diluted Net Income Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Options exercised
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercise Prices Range, Upper
Share-based Payment Arrangement, Option, Exercise Price Range, Upper Range Limit
US Government Agency Bonds [Member]
US Government Agency Bonds [Member]
US government agency bonds.
Patents
Patents [Member]
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year Three
2024
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Common stock reserved for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Retirement Plan Name
Retirement Plan Name [Domain]
Measurement Frequency
Measurement Frequency [Axis]
Award Type
Award Type [Axis]
Stock-based compensation
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-based Payment Arrangement, Percent
Disaggregation of Revenue [Abstract]
Exercise Prices Range 2
Exercise Prices Range 2 [Member]
Exercise prices range 2.
Entity Shell Company
Entity Shell Company
Marketable Securities, Long-Term [Member]
Marketable Securities, Long-Term [Member]
marketable securities, long-term.
Public offering price (in diollars per share)
Sale of Stock, Price Per Share
Common stock price per share
Success Payments Liability
Success payments liability
Success Payments Liability [Member]
Success payments liability member.
Debt Securities, Available-for-sale [Line Items]
Percentage of other party's expenses
Percentage Of Other Party S Expenses
Percentage of other party's expenses.
LIABILITIES, CONVERTIBLE PREFERRED STOCK, AND STOCKHOLDERS' EQUITY (DEFICIT)
Liabilities and Equity [Abstract]
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Weighted-Average Remaining Contractual Term (years)
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Remaining Contractual Term [Abstract]
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Remaining Contractual Term [Abstract]
Entity Incorporation State Country Code
Entity Incorporation, State or Country Code
Accrued interest on marketable securities
Marketable Securities
Marketable Securities, Total
Net Loss Per Share
Earnings Per Share [Text Block]
Clinical milestone payment
Clinical Milestone Payment
Clinical milestone payment in the feld of Human resources.
LONG-TERM LIABILITIES
Liabilities, Noncurrent [Abstract]
Accrued patent expenses
Accrued Patent Expenses Current
Accrued patent expenses.
Amendment Flag
Amendment Flag
contract assets
Contract-Based Intangible Assets [Member]
Product and Service
Product and Service [Axis]
Options granted
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Reduction Due To Options Granted In Period
Share-based compensation arrangement by share-based payment award, reduction in the number of shares available for grant due to options granted during period.
Short term investments
Short-term Investments
Short-term Investments, Total
Unrealized Losses
Available For Sale Securities Unrealized Loss
Available for sale securities unrealized loss.
Genus plc
Genus Agreement [Member]
Genus agreement.
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Other income
Other Nonoperating Income
Recent Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Exercise Price Range [Domain]
Tax Credit Carryforward, Amount
Percentage of coronavirus aid relief and economic security act removes limit for taxable years
Percentage Of Coronavirus Aid Relief And Economic Security Act Removes Limit For Taxable Years
Percentage Of coronavirus aid relief And economic security act removes limit for taxable years
Pioneer Hi-Bred International, Inc.
Pioneer Hi Bred International Inc [Member]
Pioneer Hi-Bred International, Inc.
Unrecognized stock based-compensation expenses
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Income Taxes Paid, Net
Cash paid for income taxes
Income Taxes Paid, Net, Total
Marketable securities, short-term
Marketable Securities, Current
Marketable Securities, Current, Total
Fair Value, Recurring [Member]
Fair Value, Recurring
Subsequent Events
Subsequent Events [Text Block]
2013 Stock Option Plan
Two Thousand Thirteen Stock Option Plan [Member]
Two thousand thirteen stock option plan.
Employee and Non-Employee [Member]
Employee and Non-Employee [Member]
Defined Benefit Plan Disclosure [Line Items]
Defined Benefit Plan Disclosure [Line Items]
Other assets
Other Assets, Noncurrent
Other Assets, Noncurrent, Total
Net unrealized loss on available-for-sale marketable securities
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total
Stock Available Under the Employee Stock Purchase Plan
Shares Committed Under ESPP
Employee Stock [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Geographical
Geographical [Domain]
Customer [Domain]
Unbilled accounts receivable, Deductions
Contract With Customer Assets Deductions
Contract with customer assets, deductions.
Exercisable at December 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value
Percentage of price of shares granted at fair value
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent
Schedules of Concentration of Risk, by Risk Factor [Table Text Block]
Summary Of Provision For Credit Losses and other Uncertainties
Increases related to prior year tax positions
Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions
Sale of Stock
Sale of Stock [Axis]
Finite-Lived Intangible Assets, Major Class Name
Finite-Lived Intangible Assets, Major Class Name [Domain]
Schedule of Stock-Based Compensation Expense Related to Equity-Based Awards
Share-based Payment Arrangement, Cost by Plan [Table Text Block]
Line Of Credit Facility [Table]
Line of Credit Facility [Table]
Fair Value Measurements of Financial Instruments
Fair Value Disclosures [Text Block]
Proceeds from issuance of common stock
Proceeds from Issuance of Common Stock